Robert E W Chen, MA, MSc, MB BCh, MB BChir

Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.
 

J Neurophysiol. 2014 Feb;111(3):594-601
Elahi B, Hutchison WD, Daskalakis ZJ, Gunraj C, Chen R
Handb Clin Neurol. 2013;116:375-86
Udupa K, Chen R
Exp Neurol. 2013 Dec;250:221-7
Neagu B, Tsang E, Mazzella F, Hamani C, Moro E, Hodaie M, Lozano AM, Chen R
Front Neurol. 2013 Sep 04;4:128
Udupa K, Chen R
Front Neuroeng. 2013;6:3
Golestanirad L, Elahi B, Molina A, Mosig JR, Pollo C, Chen R, Graham SJ
Nat Protoc. 2013 Jun;8(6):1184-203
Wilson NR, Schummers J, Runyan CA, Yan SX, Chen RE, Deng Y, Sur M
J Neurosci. 2013 Apr 17;33(16):6895-904
Yugeta A, Hutchison WD, Hamani C, Saha U, Lozano AM, Hodaie M, Moro E, Neagu B, Chen R
Neurology. 2013 May 07;80(19):1746-53
Ni Z, Bahl N, Gunraj CA, Mazzella F, Chen R
J Neurophysiol. 2013 Jun;109(12):2955-62
Ghosh S, Mehta AR, Huang G, Gunraj C, Hoque T, Saha U, Ni Z, Chen R
Phys Med Biol. 2012 Dec 07;57(23):7813-27
Golestanirad L, Rouhani H, Elahi B, Shahim K, Chen R, Mosig JR, Pollo C, Graham SJ

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Professor, Division of Neurology, Department of Medicine, University of Toronto