Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.

Neuropsychopharmacology. 2017 Jan;42(2):502-511
Cash RF, Noda Y, Zomorrodi R, Radhu N, Farzan F, Rajji TK, Fitzgerald PB, Chen R, Daskalakis ZJ, Blumberger DM
J Neurophysiol. 2016 Sep 01;116(3):938-48
Noda Y, Cash RF, Zomorrodi R, Dominguez LG, Farzan F, Rajji TK, Barr MS, Chen R, Daskalakis ZJ, Blumberger DM
Curr Treat Options Neurol. 2016 May;18(5):21
Levy A, Chen R
Anal Biochem. 2016 Apr 15;499:15-23
Liu L, Zhang SW, Gao F, Zhang Y, Huang Y, Chen R, Meng J
J Neurosci. 2016 Jan 13;36(2):396-404
Udupa K, Bahl N, Ni Z, Gunraj C, Mazzella F, Moro E, Hodaie M, Lozano AM, Lang AE, Chen R
Mov Disord. 2016 Jan;31(1):43
Udupa K, Chen R



Professor, Division of Neurology, Department of Medicine, University of Toronto