Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.

Adv Healthc Mater. 2015 Aug 19;:
Loynachan CN, Romero G, Christiansen MG, Chen R, Ellison R, O'Malley TT, Froriep UP, Walsh DM, Anikeeva P
Mov Disord. 2015 Sep;30(10):1326
Udupa K, Ghahremani A, Chen R
Neurology. 2015 Aug 04;85(5):425-32
Kim SJ, Udupa K, Ni Z, Moro E, Gunraj C, Mazzella F, Lozano AM, Hodaie M, Lang AE, Chen R
ACS Appl Mater Interfaces. 2015 May 27;7(20):10872-7
Ru C, Wang F, Pang M, Sun L, Chen R, Sun Y
J Physiol. 2015 Apr 01;593(7):1667-84
Cash RF, Isayama R, Gunraj CA, Ni Z, Chen R
Clin Neurophysiol. 2015 Jun;126(6):1071-107
Rossini PM, Burke D, Chen R, Cohen LG, Daskalakis Z, Di Iorio R, Di Lazzaro V, Ferreri F, Fitzgerald PB, George MS, Hallett M, Lefaucheur JP, Langguth B, Matsumoto H, Miniussi C, Nitsche MA, Pascual-Leone A, Paulus W, Rossi S, Rothwell JC, Siebner HR,...



Professor, Division of Neurology, Department of Medicine, University of Toronto