Robert E W Chen, MA, MSc, MB BCh, MB BChir

Our laboratory is currently investigating the organization of cortical inhibitory and excitatory pathways in the human motor cortex, cortical plasticity, pathophysiology of movement disorders such as Parkinson’s disease and dystonia, the mechanisms of action of deep brain stimulation as a treatment of movement disorders and inhibitory functions of the basal ganglia.

The techniques used include single pulse, paired pulse and repetitive magnetic brain stimulation; functional magnetic resonance imaging (MRI); electroencephaolgraphic (EEG) recordings of cortical rhythms and movement-related cortical potentials; magnetoencephalography (MEG); and recordings of local field potentials from deep brain stimulation electrodes in the basal ganglia.
 

J Neurophysiol. 2011 Feb;105(2):749-56
Ni Z, Charab S, Gunraj C, Nelson AJ, Udupa K, Yeh IJ, Chen R
Biol Psychiatry. 2010 Nov 01;68(9):825-31
Voineskos AN, Farzan F, Barr MS, Lobaugh NJ, Mulsant BH, Chen R, Fitzgerald PB, Daskalakis ZJ
Neurology. 2010 Sep 14;75(11):950-9
Tsang EW, Hamani C, Moro E, Mazzella F, Poon YY, Lozano AM, Chen R
Neurology. 2010 Aug 03;75(5):441-7
Nelson AJ, Hoque T, Gunraj C, Ni Z, Chen R
Mov Disord. 2010 Oct 15;25(13):2076-83
Yeh IJ, Tsang EW, Hamani C, Moro E, Mazzella F, Poon YY, Lozano AM, Chen R
Schizophr Res. 2010 Aug;121(1-3):146-52
Barr MS, Farzan F, Tran LC, Chen R, Fitzgerald PB, Daskalakis ZJ
J Neurophysiol. 2010 Sep;104(3):1339-46
Farzan F, Barr MS, Levinson AJ, Chen R, Wong W, Fitzgerald PB, Daskalakis ZJ
J Physiol. 2010 Jul 15;588(Pt 14):2633-41
Udupa K, Ni Z, Gunraj C, Chen R
Biomaterials. 2010 Aug;31(23):6096-103
Lynch AL, Chen R, Dominowski PJ, Shalaev EY, Yancey RJ, Slater NK
Brain. 2010 May;133(Pt 5):1505-14
Farzan F, Barr MS, Levinson AJ, Chen R, Wong W, Fitzgerald PB, Daskalakis ZJ

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Professor, Division of Neurology, Department of Medicine, University of Toronto