Philip J Millar

A salient feature of almost all cardiovascular diseases, and there associated risk factors, is the activation of the sympathetic nervous system. The consequences of this action are profound and impact blood pressure control, insulin sensitivity, arrhythmogenesis, and risk of sudden cardiac death. The primary aim of my research is to better understand the mechanisms that control and the functional consequences of sympathetic outflow at rest and during stress in humans with and without cardiovascular disease. To elucidate these mechanisms, I employ direct intraneural recordings of postganglionic sympathetic nerve activity, studying both multi- and single-fibre preparations. A major focus of my current work is directed at uncovering the ability of sympathetic fibres to be selectively and differentially controlled. Advancing our knowledge of these integrative mechanisms will open the doors to testing novel and clinically relevant exercise and non-exercise interventions designed to reduce sympathetic over-activation. Presently, my research is supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Canada Foundation for Innovation (CFI).
J Clin Sleep Med. 2018 Apr 15;14(4):503-510
Vena D, Bradley TD, Millar PJ, Floras JS, Rubianto J, Gavrilovic B, Perger E, Yadollahi A
J Physiol. 2018 Mar 31;:
Allwood MA, Edgett BA, Eadie AL, Huber JS, Romanova N, Millar PJ, Brunt KR, Simpson JA
J Hypertens. 2018 Jul;36(7):1477-1485
Muñoz ML, Jaju D, Voruganti S, Albarwani S, Aslani A, Bayoumi R, Al-Yahyaee S, Comuzzie AG, Millar PJ, Picton P, Floras JS, Nolte I, Hassan MO, Snieder H
J Am Soc Hypertens. 2018 Apr;12(4):275-284
Burns MJ, Seed JD, Incognito AV, Doherty CJ, Notay K, Millar PJ
J Am Heart Assoc. 2018 Jan 29;7(3):
Nardone M, Incognito AV, Millar PJ
Spinal Cord. 2018 05;56(5):469-477
van der Scheer JW, Kamijo YI, Leicht CA, Millar PJ, Shibasaki M, Goosey-Tolfrey VL, Tajima F
Sleep. 2017 Dec 23;:
Taylor KS, Millar PJ, Murai H, Haruki N, Kimmerly DS, Bradley TD, Floras JS
Med Sci Sports Exerc. 2018 May;50(5):928-937
Coates AM, Incognito AV, Seed JD, Doherty CJ, Millar PJ, Burr JF
Med Sci Sports Exerc. 2018 Apr;50(4):778-784
Notay K, Lee JB, Incognito AV, Seed JD, Arthurs AA, Millar PJ


Assistant Professor, Human Health & Nutritional Sciences, University of Guelph
Adjunct faculty, School of Health and Human Performance, Dalhousie University