Laura Middleton, PhD

Cognition abilities contribute to educational and occupational achievement, daily function and motor performance. Unfortunately, cognitive performance declines on average in late life and the prevalence of dementia nearly doubles every five years after the age of 65 years. Over a million people in Canada will have dementia within a generation, as more people live to ages when dementia is common. My research aims to identify ways to optimize cognition across the life course and to prevent dementia in late life. In particular, I investigate the relationship between physical exercise, cognition and brain function using techniques from several disciplines including neuroscience, exercise physiology and epidemiology.
BMC Geriatr. 2018 Apr 16;18(1):93
Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L,...
BMJ Open. 2018 03 17;8(3):e021490
Best JR, Eng JJ, Davis JC, Hsiung R, Hall PA, Middleton LE, Graf P, Goldsmith CH, Liu-Ambrose T
BMC Geriatr. 2018 01 25;18(1):27
Middleton LE, Black SE, Herrmann N, Oh PI, Regan K, Lanctot KL
Contemp Clin Trials. 2017 Oct 21;:
Middleton LE, Ventura MI, Santos-Modesitt W, Poelke G, Yaffe K, Barnes DE
Front Aging Neurosci. 2017;9:318
Robertson AD, Marzolini S, Middleton LE, Basile VS, Oh PI, MacIntosh BJ
J Stroke Cerebrovasc Dis. 2017 Jul 31;:
Swatridge K, Regan K, Staines WR, Roy E, Middleton LE
BMJ Open. 2017 Jun 30;7(6):e015843
Mansfield A, Brooks D, Tang A, Taylor D, Inness EL, Kiss A, Middleton L, Biasin L, Fleck R, French E, LeBlanc K, Aqui A, Danells C
BMC Public Health. 2017 Feb 17;17(1):209
Ginis KA, Heisz J, Spence JC, Clark IB, Antflick J, Ardern CI, Costas-Bradstreet C, Duggan M, Hicks AL, Latimer-Cheung AE, Middleton L, Nylen K, Paterson DH, Pelletier C, Rotondi MA
Neuroscience. 2017 Jan 21;:
Beyer KB, D Sage M, Richard Staines W, Middleton LE, McIlroy WE
Can J Aging. 2016 Dec;35(4):526-532
Regan K, Intzandt B, Swatridge K, Myers A, Roy E, Middleton LE


Assistant Professor, Department of Kinesiology, University of Waterloo
Associate Scientist, Canadian Partnership for Stroke Recovery