Dr. Jinzi Zheng is a Scientist at the TECHNA Institute for the Advancement of Technologies for Health, University Health Network (UHN) and an Assistant Professor at the Institute of Biomaterials and Biomedical Engineering (IBBME), University of Toronto. She received her Bachelor’s degree in Applied Science and Engineering (Engineering Science, Biomedical Engineering Option) and her PhD in Medical Biophysics from the University of Toronto. She completed her post-doctoral training at the French Atomic Energy Commission (CEA) and the French National Institute of Health and Medical Research (INSERM). Jinzi’s research focuses on the development of new nanotechnology platforms for image-guided cancer therapy. She has been the recipient of over 20 awards and is dedicated to translating effective research innovations to improve patient care.
Imaging technologies are being increasingly employed to guide the delivery of cancer therapies with the intent to increase their performance and efficacy. To date, many patients have benefited from image-guided treatments through prolonged survival and improvements in quality of life. Our research is focused on the development of agents and tools that can further increase the performance of imaging in the therapy-guidance context. Specifically, we are active in the areas of image-guided surgery, personalized nanomedicine delivery, tracking of cell therapies and high-precision radiotherapy delivery.
Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis.
Gastroenterology. 2017 Nov 10;:
Rapid Detection of Necrosis in Breast Cancer with Desorption Electrospray Ionization Mass Spectrometry.
Sci Rep. 2016 Oct 13;6:35374
PLoS One. 2016;11(9):e0161991
Spatial Measurements of Perfusion, Interstitial Fluid Pressure and Liposomes Accumulation in Solid Tumors.
J Vis Exp. 2016;(114)
Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance.
J Vis Exp. 2015;(106)
Ambient Mass Spectrometry Imaging with Picosecond Infrared Laser Ablation Electrospray Ionization (PIR-LAESI).
Anal Chem. 2015 Nov 23;
Longitudinal tumor hypoxia imaging with [(18)F]FAZA-PET provides early prediction of nanoliposomal irinotecan (nal-IRI) treatment activity.
EJNMMI Res. 2015 Dec;5(1):57
Biomaterials. 2015 Oct;67:160-8
Evaluation of PET Imaging Performance of the TSPO Radioligand [(18)F]DPA-714 in Mouse and Rat Models of Cancer and Inflammation.
Mol Imaging Biol. 2015 Jul 21;
Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302).
Mol Cancer Ther. 2015 Sep;14(9):2060-71
Research Faculty, Techna Institute for the Advancement of Technology for Health (Techna)
Assistant Professor, Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto