- Lineage specific differentiation of embryonic stem (ES) cells in culture
- Development of the hematopoietic, vascular, and cardiac lineages from ES cells
- Commitment of ES cells to endoderm-derived lineages
- Growth and differentiation of human embryonic stem cells
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.
Development. 2011 Mar;138(5):861-71
Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells.
Development. 2010 Sep 1;137(17):2829-39
Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells.
Stem Cells. 2010 Mar 31;28(3):620-32
Directed differentiation of hematopoietic precursors and functional osteoclasts from human ES and iPS cells.
Blood. 2010 Apr 8;115(14):2769-76
The homeobox gene Hex regulates hepatocyte differentiation from embryonic stem cell-derived endoderm.
Hepatology. 2010 Feb;51(2):633-41
The cardiomyocyte lineage is critical for optimization of stem cell therapy in a mouse model of myocardial infarction.
FASEB J. 2010 Apr;24(4):1073-81
Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue.
Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3329-34
In vivo detection of embryonic stem cell-derived cardiovascular progenitor cells using Cy3-labeled Gadofluorine M in murine myocardium.
JACC Cardiovasc Imaging. 2009 Sep;2(9):1114-22
Directed differentiation of pluripotent stem cells: from developmental biology to therapeutic applications.
Cold Spring Harb Symp Quant Biol. 2008;73:101-10
Cell Stem Cell. 2009 Mar 6;4(3):198-9; author reply 202
Senior Scientist, Princess Margaret Cancer Centre
Director, McEwen Centre for Regenerative Medicine, University Health Network
Lead Scientist, Centre for Commercialization of Regenerative Medicine
Professor, Department of Medical Biophysics, University of Toronto