- Lineage specific differentiation of embryonic stem (ES) cells in culture
- Development of the hematopoietic, vascular, and cardiac lineages from ES cells
- Commitment of ES cells to endoderm-derived lineages
- Growth and differentiation of human embryonic stem cells
Dev Cell. 2014 Dec 30;
Transforming the Promise of Pluripotent Stem Cell-Derived Cardiomyocytes to a Therapy: Challenges and Solutions for Clinical Trials.
Can J Cardiol. 2014 Nov;30(11):1335-1349
Nat Biotechnol. 2014 Oct;32(10):1026-35
Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells.
Nat Biotechnol. 2014 Jun;32(6):554-61
The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes.
Biomaterials. 2014 Mar;35(9):2798-808
Lab Chip. 2014 Mar 7;14(5):869-82
Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4698-707
Cell. 2013 Sep 26;155(1):215-27
Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation.
Am J Pathol. 2013 Sep;183(3):720-34
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes.
Development. 2013 Aug;140(15):3285-96
Senior Scientist, Princess Margaret Cancer Centre
Director, McEwen Centre for Regenerative Medicine, University Health Network
Lead Scientist, Centre for Commercialization of Regenerative Medicine
Professor, Department of Medical Biophysics, University of Toronto