Donald R Branch

Donald R Branch, PhD

Dr. Branch's current interests can be broken down into 4 main areas:
  • Signaling involving c-Src
  • Signaling in HIV/AIDS pathogenesis and disease resistance
  • Studies of SHP-1 tyrosine phosphatase in malignancies
  • Mechanism of intravenous immunoglobulin (IVIG) effect in autoimmune inflammatory diseases
Current projects include:
  • The function of pp60c-src and Pyk2 in HIV infection 
  • The role of signaling through the VPAC family of neuroendocrine receptors on HIV/AIDS infection and resistance to infection 
  • Drug discovery for small molecular weight molecules that block HIV fusion 
  • Identification of novel treatment modalities for HIV/AIDS 
  • The signaling pathways used by HIV for its early stages of its life cycle 
  • The mechanism of IVIG treatment for autoimmune inflammatory diseases 
  • Drug discovery for small molecular weight molecules that inhibit phagocytosis 
  • The mechanism of anti-D immune prophylaxis and treatment of idiopathic thrombocytopenic purpura
  • Drug discovery for alternatives to IVIG
Sci Rep. 2017 May 02;7(1):1296
Schneider C, Wicki S, Graeter S, Timcheva TM, Keller CW, Quast I, Leontyev D, Djoumerska-Alexieva IK, Käsermann F, Jakob SM, Dimitrova PA, Branch DR, Cummings RD, Lünemann JD, Kaufmann T, Simon HU, von Gunten S
J Liposome Res. 2017 Mar 09;:1-9
da Silveira Cavalcante L, Branch DR, Duong TT, Yeung RS, Acker JP, Holovati JL
Virology. 2016 Dec 22;502:73-83
Le Sage V, Cinti A, McCarthy S, Amorim R, Rao S, Daino GL, Tramontano E, Branch DR, Mouland AJ
Transfusion. 2016 Dec;56(12):2913-2915
Branch DR, Westhoff CM
Blood. 2016 Sep 29;
Liu J, Santhanakrishnan M, Natarajan P, Gibb DR, Eisenbarth SC, Tormey CA, Siddon AJ, Stowell SR, Branch DR, Hendrickson JE
Transfusion. 2016 Aug 21;
Tong TN, Burke-Murphy E, Sakac D, Pendergrast J, Cserti-Gazdewich C, Laroche V, Branch DR
Autoimmun Rev. 2016 Jun 11;
Neschadim A, Kotra LP, Branch DR
AIDS. 2016 May 17;
Kozlowski HN, Lai ET, Havugimana PC, White C, Emili A, Sakac D, Binnington B, Neschadim A, Mccarthy SD, Branch DR
Transfus Med. 2016 May 4;
Tong TN, Cserti-Gazdewich CM, Branch DR

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Associate Professor, Department of Laboratory Medicine and Pathobiology, University of Toronto
Scientist, Canadian Blood Services