New research findings are reported in NRx (formerly known as Net Results Express)—the UHN Research e-newsletter that is distributed monthly to all UHN employees and is made publicly available through the UHN Twitter and Facebook pages.
April 2013
Liver Disease: A New Approach in the Treatment of Hepatitis C
Urology: Prevention of Prostate Disorder Symptoms
Eye Disease: A New Mechanism that Regulates Cell Death in the Retina
Parkinson’s Disease: Unravelling Crossed Signals
Lung Transplantation: Preventing Rejection with Gene Therapy
Rehabilitation: Measuring Balance
March 2013
Neuroscience: Treating Anorexia with Deep Brain Stimulation
Cancer: The Causes of Tumours of the Eye
Cancer: Targeting Hypoxia Tolerance for Improved Cancer Therapy
Diabetes: Glucagon Response to Fasting and Starvation
Rehabilitation: Referral Strategies for Women with Heart Disease
February 2013
Obesity: The Role of Intestinal Bacteria in Fatty Liver Disease
Leukemia: Stem Cell Transplant Therapy for AML
Drug Development: New Directions in the Treatment of Multiple Sclerosis
Arthritis: The Challenge of Integrating Physical Activity into Daily Life
Stroke: Regaining Balance with Visual Cues
January 2013
Respiration: Testing a New Model to Treat Lung Injury
Cancer: New Discovery for Tumour Growth
Cancer: Refining Treatment of Oropharyngeal Cancer
Obesity: Protecting the Heart from a High Fat Diet
Cardiology: Effect of Sleep Apnea on Heart Function
Genetics: Understanding How Drugs Affect the Entire System
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December 2012: Year in Review
November 2012
Heart Disease: Treating Patients Diagnosed with Diabetes
Cancer: Palliative Care Referral Practices in Oncology
Cancer: Novel Imaging and Therapeutic In One Tiny Package
Bipolar Disorder: Insulin Improves the Mental Performance of Bipolar Patients
Sleep Apnea: Making Waves in the Link to Renal Disease
October 2012
Cancer: A Single DNA Nucleotide Difference Regulates Breast Cancer Cell Growth
Diabetes: The Role of the Brain in Insulin Resistance
Malaria: Blood Type Influences Disease Severity
Stroke: An Experimental Model Accurately Predicts the Outcomes of a Therapeutic Stroke Drug
Genetics: Protein Levels Associated with Behavioural Impairments
Heart Disease: Timing of Depression on Patient Outcomes
September 2012
UHN Licenses Cancer Treatment Planning Technology to RaySearch Laboratories
Cancer: Characterizing the Effect of Genetic Variants in Neuroendocrine Cancers
Osteoporosis: Inaccurate Assessment of Fracture Risk in Ontario’s Non-Urban Areas
Immunology: Insights into HIV Susceptibility
SCRIPDB Partners with NIH PubChem
August 2012
Cancer: Molecular Mechanisms of Cellular Polarity
Medical Imaging: First Microbubble with Inherent Dual Imaging Properties
Leukemia: A New Molecular Target for Therapy
Medical Care: How Surgical Culture Affects Error
Respiration: New Educational Objectives for Mechanical Ventilation Practice
Rehabilitation: Measuring Activity with Brain Computer Interface Systems
July 2012
Leukemia: An Experimental Model for AML Provides New Insights
Cancer Care: Drug Development and Maintaining Quality of Life
Rheumatoid Arthritis: Circulating Non-Immune Cells Promote the Spread of Joint Inflammation
Bipolar Disorder: Making Beneficial Therapy More Accessible
Exercise: Improving Quality of Life in Patients Undergoing Chemotherapy
Computational Neuroscience: The Relationship between Individual Neurons and Population Network Activities in the Hippocampus
June 2012
Colon Cancer: Understanding Self Renewal and Resistance
Patient Care: A Better Predictor of Heart Failure in Emergency Room Care
Prostate Cancer: Seeking Out Genetic Variations that Increase Cancer Risk
Pancreatitis: How Alcohol Damages the Pancreas
Health Outcomes: Chronic Joint Pain in the Canadian Population
Influenza: Identifying Risk of Severe Illness
May 2012
Kidney Failure: Fish Oils May Provide Benefits for Hemodialysis Patients
Diabetes: Glucose Regulation by the Intestine
Autoimmunity: Gender Differences in the Immune System
Hypertension: Managing Blood Pressure with Your Smartphone
Sleep Apnea: Daytime Alertness may Reveal Heart Health
Neurology: Exploring the Regulation of Brain Function
April 2012
Cancer: A New Understanding of Immune System Responses
Breast Cancer: Gene Signatures for Better Treatments
Spinal Cord Injury: Reducing Inflammation with a Smart Material
Diabetes: New Insight into Insulin Release
Prostate Cancer: Predicting Recurrence using Oxygen Levels
Stroke Rehabilitation: Determining Fall Prevention Responses in Stroke Patients
March 2012
Stroke: Development of World’s Most Advanced Neuroprotective Drug
Proteomics: A Novel Method to Identify Stem Cell Types
Medical Imaging: Novel Tools for Visualizing Tumours Using Nanotechnology
Metabolism: Appetite Control in the Brain
Rehabilitation: Psychotherapy Promotes Prolonged Benefits in Patients with Brain Injury
UHN Licensed Image Guided Irradiator System Reaches 10th Installation Milestone
February 2012
Structural Biology: Looking Into the Mechanics of Calcium Release
Development: Imprinting in the Mouse Genome
Breast Cancer: Risks and Benefits of Prevention
Neurology: Controlling the Growth of Neurons
Stroke: Exercise Program for Rehabilitation
Cancer: Preventing Tumours in Retinoblastoma
January 2012
Ovarian Cancer: Drug Delays Disease Progression
Immunity: Regulating the Response to Infection
Hormone Therapy: Ontario Failing to Treat Osteoporosis-Related Side Effects
Metabolism: How the Gut Controls Glucose Production
Immunology: A New Model for Injury Repair in the Eye
Social Media: The Role of Twitter in Assessing Scientific Impact
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December 2011: Year in Review
November 2011
UHN and University of Toronto Launch Techna Institute
iDAPT: World Class Innovation at Toronto Rehab
Prostate Cancer: Combination Treatment Greatly Improves Survival
Cardiology: Sodium Intake Increases Risk of Sleep Apnea
UHN Educational Tool Licensed to Edwards Lifesciences
Inflammatory Arthritis: Identifying Risk of Disease Progression
October 2011
PMH Awarded Third National Cancer Institute Contract
Immune Disorders: New Insights into Cell Regulation
Immunity: Cell Adhesion in Leukocytes
Neurology: Uncovering Factors Associated with the Development of Neurons
Clinical Trials: The Impact of Announcements on Company Stock Prices
Alzheimer’s Disease: Quality of Life Assessed by Family Caregivers
September 2011
UHN Medical Imaging Tool Licensed to Vexim SA
Cancer: Creating a Blueprint of Protein Modifications
Cardiology: Distinguishing the Mechanisms of Heart Contraction
Psoriatic Arthritis: The Disease within a Disease
Pulmonary Disease: Increasing Physical Activity
Nanomedicine: Delivery of Anticancer Drugs
Cardiology: Reducing Inflammation in Damaged Cardiac Muscle
Stroke Prevention: Assessing the Effects of Surgical Revascularization
August 2011
Strategic Planning Needs Your Help
Autoimmune Diseases: Explaining the Role of PTPN22 in Immunity
Leukemia: Stem Cell Properties Correlate with Disease Outcome
Immunity: Identifying the Mechanisms Involved in Inflammation of the Colon
Spondyloarthritis: Impact on Social Life
Radioisotope Therapy: The Future of Antibody Linked Radiotherapy
Osteoporosis: Better Prevention from Future Injury
July 2011
UHN's New Office of Research Trainees
Stem Cells: Isolation of the Purest Blood Stem Cells
Clinical Trials: Assessing the Effects of Unpublished Data
Gastroenterology: New Insights into Blood Glucose Regulation
Blood: New Directions for Disease Treatment
Stroke: Understanding the Short-Term Outcomes for Artery Blockage
June 2011
UHN and Toronto Rehabilitation Institute Announce Their Integration
Neurology: Stimulation of the Motor Cortex Improves Hand Tremors
Leukemia: New Cancer Stem Cell Factor Identified
Cardiology: New Role for Protein in Heart Function
Myeloma: Antitumour Activity with New Therapeutic Drug
Stem Cells: Characterizing Neural Stem Cell Development
May 2011
Health Services Research at UHN: Strategic Planning Workshop
Prostate Cancer: New Findings on the Effects of Supplements
Cancer: A New Mechanism for Resistance to Therapy
Leukemia: Helping the Immune System Fight Cancer
Parkinson’s Disease: Enhancing the Therapeutic Benefits of L-DOPA
Neuroscience: Understanding the Effect of Seizures in Stroke Patients
Acute Lung Injury: New Insight into Factors Involved in Cell and Tissue Damage
April 2011
Lung Transplantation: High-Risk Donor Lungs Can Now Be Safely Used for Transplant
Respiratory Disease: Long-Term Study on the Effects of Acute Illness
Lung Cancer: Changes in Non-Cancer Cells May Predict Patient Outcome
Diabetes: New Guidelines for Treating Diabetic Neuropathy
Neurology: Surgical Procedure Reverses Loss of Brain Matter
Autoimmune Disease: New Suppressor Gene Discovered in Lupus-Prone Mice
March 2011
Cancer: Novel Organic Nanoparticles for Cancer Targeting and Treatment
Cardiology: Novel Peptide Helps to Prevent Damage Following Cardiovascular Injury
Pancreatic Cancer: Hypoxia Predicts Growth and Metastasis
Stroke: Why Sleeping Better is Good for Stroke Patients
Intracerebral Hemorrhage: Identifying a Culprit in Brain Injury
Arthritis: Examining Workplace Activity Limitations
February 2011
Leukemia: Uncovering Genetic Diversity in Propagating Cells
HIV Infection: Promoting the Immune Response to Chronic Viral Infections
Regenerative Medicine: Development of Heart Cells from Stem Cells
Depression: Deep Brain Stimulation Shows Benefit in 3 and 6 Year Follow-Up Study
Parkinson Disease: New Insights into the Role of the Cerebellum in Disease Development
Heart Disease: A Novel Mechanism of Electrical Remodeling in Cardiac Hypertrophy and Heart Failure
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December 2010: Year in Review
October 2010
Cancer: Identifying the Cells that Cause Cancer
Lung Cancer: Gene Signature Helps Predict Benefits of Chemotherapy
Neuroscience: The Cellular Basis of Neural Impulse Transmission
Heart Disease: Preventing Injury Following Transplantation
Diabetes: Detecting Sugar Sensing Pathways in the Brain
Virology: Developing New Methods to Fight off SARS
Parkinson's Disease: Learning the Benefits of Combined Therapy
September 2010
Primary Biliary Cirrhosis: Confirming Gene Involvement
Leukemia: Timing DNA Repair and Cell Death to Prevent Cancer
Alzheimer's Disease: Investigating New Stimulating Treatment Techniques
Neurology: Understanding How Perception of Pain Affects Recovery
July 2010
Influenza A: Identifying New Cell Populations to Battle Disease
Immunity and Disease: Applying Cell Therapy to Combat Infectious Disease
Hodgkin Lymphoma: Investigating Heart Disease Risk and Cancer Treatment
Lupus: Monitoring Heart Disease Risk in Patients
Parkinson’s Disease: Understanding the Anatomy of Movement
June 2010
ELLICSR Opens its Doors
Immune System: Revising the ‘Road Map’ of Blood Development
Malignant Mesothelioma: Identifying New Investigative Tools
Cancer: Depression in Patients with Advanced Disease
Neurology: Targeting Brain Communication Circuits to Understand Disease
May 2010
UHN Captures $30M in New Ministry Funding
Breast Cancer: Hormone-Driven Cell Growth
Irritable Bowel Syndrome: Brain Landscape Changes and Disrupted Communication
Neurology: Determining When to Re-Start Anticoagulation
Diabetes: Locating the Brain’s ‘Sweet Spot’
April 2010
Structural biology: Understanding How Cells Anchor
Malaria: How Maternal Infection Contributes to Low Birth Weight
Lymphoma: Opening the Door to New Research and Treatments
Lung Cancer: Economic Analysis of Targeted Therapy
Parkinson's Disease: Learning the Long-Term Effects of Deep Brain Stimulation
March 2010
Lupus: Investigating Antimalarial Treatments
Head and Neck Cancer: Using Global Screens for New Target Identification
Lung Injury: Getting to the Bottom of Injury Promotion and Prevention
Neurology: Establishing a Circulation and Brain Landscape Relationship
February 2010
Leukemia: Elucidating Genetic Areas of Control
Heart Failure: Tracking Patients after Discharge
Cancer: Understanding Timing and Tumor Development
Liver Transplant: Determining When and Why to Apply the Surgical Brakes
Regenerative Medicine: Repairing the Injured Spinal Cord
Rett Syndrome: Surveying Brain Patterns to Increase Disease Knowledge
January 2010
Cancer: Changing Current Understanding of Gene Function
Leukemia: New Population of Cells Discovered
Cancer Biology: Sensitizing ‘Tenacious’ Tumour Cells
Neurology: Detailing the Memory Process
Cardiology: Re-Examining Protective Properties of Beta-Blockers
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Net Results EXPRESS archive .
