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New research findings are reported in NRx (formerly known as Net Results Express)—the UHN Research e-newsletter that is distributed monthly to all UHN employees and is made publicly available through the UHN Twitter and Facebook pages.

Current and past issues of NRx are linked below (in HTML format):

April 2013

  • Liver Disease: A New Approach in the Treatment of Hepatitis C
  • Urology: Prevention of Prostate Disorder Symptoms
  • Eye Disease: A New Mechanism that Regulates Cell Death in the Retina
  • Parkinson’s Disease: Unravelling Crossed Signals
  • Lung Transplantation: Preventing Rejection with Gene Therapy
  • Rehabilitation: Measuring Balance

March 2013

  • Neuroscience: Treating Anorexia with Deep Brain Stimulation
  • Cancer: The Causes of Tumours of the Eye
  • Cancer: Targeting Hypoxia Tolerance for Improved Cancer Therapy
  • Diabetes: Glucagon Response to Fasting and Starvation
  • Rehabilitation: Referral Strategies for Women with Heart Disease

February 2013

  • Obesity: The Role of Intestinal Bacteria in Fatty Liver Disease
  • Leukemia: Stem Cell Transplant Therapy for AML
  • Drug Development: New Directions in the Treatment of Multiple Sclerosis
  • Arthritis: The Challenge of Integrating Physical Activity into Daily Life
  • Stroke: Regaining Balance with Visual Cues

January 2013

  • Respiration: Testing a New Model to Treat Lung Injury
  • Cancer: New Discovery for Tumour Growth
  • Cancer: Refining Treatment of Oropharyngeal Cancer
  • Obesity: Protecting the Heart from a High Fat Diet
  • Cardiology: Effect of Sleep Apnea on Heart Function
  • Genetics: Understanding How Drugs Affect the Entire System

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December 2012: Year in Review

November 2012

  • Heart Disease: Treating Patients Diagnosed with Diabetes
  • Cancer: Palliative Care Referral Practices in Oncology
  • Cancer: Novel Imaging and Therapeutic In One Tiny Package
  • Bipolar Disorder: Insulin Improves the Mental Performance of Bipolar Patients
  • Sleep Apnea: Making Waves in the Link to Renal Disease

October 2012

  • Cancer: A Single DNA Nucleotide Difference Regulates Breast Cancer Cell Growth
  • Diabetes: The Role of the Brain in Insulin Resistance
  • Malaria: Blood Type Influences Disease Severity
  • Stroke: An Experimental Model Accurately Predicts the Outcomes of a Therapeutic Stroke Drug
  • Genetics: Protein Levels Associated with Behavioural Impairments
  • Heart Disease: Timing of Depression on Patient Outcomes

September 2012

  • UHN Licenses Cancer Treatment Planning Technology to RaySearch Laboratories
  • Cancer: Characterizing the Effect of Genetic Variants in Neuroendocrine Cancers
  • Osteoporosis: Inaccurate Assessment of Fracture Risk in Ontario’s Non-Urban Areas
  • Immunology: Insights into HIV Susceptibility
  • SCRIPDB Partners with NIH PubChem

August 2012

  • Cancer: Molecular Mechanisms of Cellular Polarity
  • Medical Imaging: First Microbubble with Inherent Dual Imaging Properties
  • Leukemia: A New Molecular Target for Therapy
  • Medical Care: How Surgical Culture Affects Error
  • Respiration: New Educational Objectives for Mechanical Ventilation Practice
  • Rehabilitation: Measuring Activity with Brain Computer Interface Systems

July 2012

  • Leukemia: An Experimental Model for AML Provides New Insights
  • Cancer Care: Drug Development and Maintaining Quality of Life
  • Rheumatoid Arthritis: Circulating Non-Immune Cells Promote the Spread of Joint Inflammation
  • Bipolar Disorder: Making Beneficial Therapy More Accessible
  • Exercise: Improving Quality of Life in Patients Undergoing Chemotherapy
  • Computational Neuroscience: The Relationship between Individual Neurons and Population Network Activities in the Hippocampus

June 2012

  • Colon Cancer: Understanding Self Renewal and Resistance
  • Patient Care: A Better Predictor of Heart Failure in Emergency Room Care
  • Prostate Cancer: Seeking Out Genetic Variations that Increase Cancer Risk
  • Pancreatitis: How Alcohol Damages the Pancreas
  • Health Outcomes: Chronic Joint Pain in the Canadian Population
  • Influenza: Identifying Risk of Severe Illness

May 2012

  • Kidney Failure: Fish Oils May Provide Benefits for Hemodialysis Patients
  • Diabetes: Glucose Regulation by the Intestine
  • Autoimmunity: Gender Differences in the Immune System
  • Hypertension: Managing Blood Pressure with Your Smartphone
  • Sleep Apnea: Daytime Alertness may Reveal Heart Health
  • Neurology: Exploring the Regulation of Brain Function

April 2012

  • Cancer: A New Understanding of Immune System Responses
  • Breast Cancer: Gene Signatures for Better Treatments
  • Spinal Cord Injury: Reducing Inflammation with a Smart Material
  • Diabetes: New Insight into Insulin Release
  • Prostate Cancer: Predicting Recurrence using Oxygen Levels
  • Stroke Rehabilitation: Determining Fall Prevention Responses in Stroke Patients

March 2012

  • Stroke: Development of World’s Most Advanced Neuroprotective Drug
  • Proteomics: A Novel Method to Identify Stem Cell Types
  • Medical Imaging: Novel Tools for Visualizing Tumours Using Nanotechnology
  • Metabolism: Appetite Control in the Brain
  • Rehabilitation: Psychotherapy Promotes Prolonged Benefits in Patients with Brain Injury
  • UHN Licensed Image Guided Irradiator System Reaches 10th Installation Milestone

February 2012

  • Structural Biology: Looking Into the Mechanics of Calcium Release
  • Development: Imprinting in the Mouse Genome
  • Breast Cancer: Risks and Benefits of Prevention
  • Neurology: Controlling the Growth of Neurons
  • Stroke: Exercise Program for Rehabilitation
  • Cancer: Preventing Tumours in Retinoblastoma

January 2012

  • Ovarian Cancer: Drug Delays Disease Progression
  • Immunity: Regulating the Response to Infection
  • Hormone Therapy: Ontario Failing to Treat Osteoporosis-Related Side Effects
  • Metabolism: How the Gut Controls Glucose Production
  • Immunology: A New Model for Injury Repair in the Eye
  • Social Media: The Role of Twitter in Assessing Scientific Impact

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December 2011: Year in Review

November 2011

  • UHN and University of Toronto Launch Techna Institute
  • iDAPT: World Class Innovation at Toronto Rehab
  • Prostate Cancer: Combination Treatment Greatly Improves Survival
  • Cardiology: Sodium Intake Increases Risk of Sleep Apnea
  • UHN Educational Tool Licensed to Edwards Lifesciences
  • Inflammatory Arthritis: Identifying Risk of Disease Progression

October 2011

  • PMH Awarded Third National Cancer Institute Contract
  • Immune Disorders: New Insights into Cell Regulation
  • Immunity: Cell Adhesion in Leukocytes
  • Neurology: Uncovering Factors Associated with the Development of Neurons
  • Clinical Trials: The Impact of Announcements on Company Stock Prices
  • Alzheimer’s Disease: Quality of Life Assessed by Family Caregivers

September 2011

  • UHN Medical Imaging Tool Licensed to Vexim SA
  • Cancer: Creating a Blueprint of Protein Modifications
  • Cardiology: Distinguishing the Mechanisms of Heart Contraction
  • Psoriatic Arthritis: The Disease within a Disease
  • Pulmonary Disease: Increasing Physical Activity
  • Nanomedicine: Delivery of Anticancer Drugs
  • Cardiology: Reducing Inflammation in Damaged Cardiac Muscle
  • Stroke Prevention: Assessing the Effects of Surgical Revascularization

August 2011

  • Strategic Planning Needs Your Help
  • Autoimmune Diseases: Explaining the Role of PTPN22 in Immunity
  • Leukemia: Stem Cell Properties Correlate with Disease Outcome
  • Immunity: Identifying the Mechanisms Involved in Inflammation of the Colon
  • Spondyloarthritis: Impact on Social Life
  • Radioisotope Therapy: The Future of Antibody Linked Radiotherapy
  • Osteoporosis: Better Prevention from Future Injury

July 2011

  • UHN's New Office of Research Trainees
  • Stem Cells: Isolation of the Purest Blood Stem Cells
  • Clinical Trials: Assessing the Effects of Unpublished Data
  • Gastroenterology: New Insights into Blood Glucose Regulation
  • Blood: New Directions for Disease Treatment
  • Stroke: Understanding the Short-Term Outcomes for Artery Blockage

June 2011

  • UHN and Toronto Rehabilitation Institute Announce Their Integration
  • Neurology: Stimulation of the Motor Cortex Improves Hand Tremors
  • Leukemia: New Cancer Stem Cell Factor Identified
  • Cardiology: New Role for Protein in Heart Function
  • Myeloma: Antitumour Activity with New Therapeutic Drug
  • Stem Cells: Characterizing Neural Stem Cell Development

May 2011

  • Health Services Research at UHN: Strategic Planning Workshop
  • Prostate Cancer: New Findings on the Effects of Supplements
  • Cancer: A New Mechanism for Resistance to Therapy
  • Leukemia: Helping the Immune System Fight Cancer
  • Parkinson’s Disease: Enhancing the Therapeutic Benefits of L-DOPA
  • Neuroscience: Understanding the Effect of Seizures in Stroke Patients
  • Acute Lung Injury: New Insight into Factors Involved in Cell and Tissue Damage

April 2011

  • Lung Transplantation: High-Risk Donor Lungs Can Now Be Safely Used for Transplant
  • Respiratory Disease: Long-Term Study on the Effects of Acute Illness
  • Lung Cancer: Changes in Non-Cancer Cells May Predict Patient Outcome
  • Diabetes: New Guidelines for Treating Diabetic Neuropathy
  • Neurology: Surgical Procedure Reverses Loss of Brain Matter
  • Autoimmune Disease: New Suppressor Gene Discovered in Lupus-Prone Mice

March 2011

  • Cancer: Novel Organic Nanoparticles for Cancer Targeting and Treatment
  • Cardiology: Novel Peptide Helps to Prevent Damage Following Cardiovascular Injury
  • Pancreatic Cancer: Hypoxia Predicts Growth and Metastasis
  • Stroke: Why Sleeping Better is Good for Stroke Patients
  • Intracerebral Hemorrhage: Identifying a Culprit in Brain Injury
  • Arthritis: Examining Workplace Activity Limitations

February 2011

  • Leukemia: Uncovering Genetic Diversity in Propagating Cells
  • HIV Infection:  Promoting the Immune Response to Chronic Viral Infections
  • Regenerative Medicine: Development of Heart Cells from Stem Cells
  • Depression: Deep Brain Stimulation Shows Benefit in 3 and 6 Year Follow-Up Study
  • Parkinson Disease: New Insights into the Role of the Cerebellum in Disease Development
  • Heart Disease: A Novel Mechanism of Electrical Remodeling in Cardiac Hypertrophy and Heart Failure

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December 2010: Year in Review

October 2010

  • Cancer: Identifying the Cells that Cause Cancer
  • Lung Cancer: Gene Signature Helps Predict Benefits of Chemotherapy
  • Neuroscience: The Cellular Basis of Neural Impulse Transmission
  • Heart Disease: Preventing Injury Following Transplantation
  • Diabetes: Detecting Sugar Sensing Pathways in the Brain
  • Virology: Developing New Methods to Fight off SARS
  • Parkinson's Disease: Learning the Benefits of Combined Therapy

September 2010

  • Primary Biliary Cirrhosis: Confirming Gene Involvement
  • Leukemia: Timing DNA Repair and Cell Death to Prevent Cancer
  • Alzheimer's Disease: Investigating New Stimulating Treatment Techniques
  • Neurology: Understanding How Perception of Pain Affects Recovery

July 2010

  • Influenza A: Identifying New Cell Populations to Battle Disease
  • Immunity and Disease: Applying Cell Therapy to Combat Infectious Disease
  • Hodgkin Lymphoma: Investigating Heart Disease Risk and Cancer Treatment
  • Lupus: Monitoring Heart Disease Risk in Patients
  • Parkinson’s Disease: Understanding the Anatomy of Movement

June 2010

  • ELLICSR Opens its Doors
  • Immune System: Revising the ‘Road Map’ of Blood Development
  • Malignant Mesothelioma: Identifying New Investigative Tools
  • Cancer: Depression in Patients with Advanced Disease
  • Neurology: Targeting Brain Communication Circuits to Understand Disease

May 2010

  • UHN Captures $30M in New Ministry Funding
  • Breast Cancer: Hormone-Driven Cell Growth
  • Irritable Bowel Syndrome: Brain Landscape Changes and Disrupted Communication
  • Neurology: Determining When to Re-Start Anticoagulation
  • Diabetes: Locating the Brain’s ‘Sweet Spot’

April 2010

  • Structural biology: Understanding How Cells Anchor
  • Malaria: How Maternal Infection Contributes to Low Birth Weight
  • Lymphoma: Opening the Door to New Research and Treatments
  • Lung Cancer: Economic Analysis of Targeted Therapy
  • Parkinson's Disease: Learning the Long-Term Effects of Deep Brain Stimulation

March 2010

  • Lupus: Investigating Antimalarial Treatments
  • Head and Neck Cancer: Using Global Screens for New Target Identification
  • Lung Injury: Getting to the Bottom of Injury Promotion and Prevention
  • Neurology: Establishing a Circulation and Brain Landscape Relationship

February 2010

  • Leukemia: Elucidating Genetic Areas of Control
  • Heart Failure: Tracking Patients after Discharge
  • Cancer: Understanding Timing and Tumor Development
  • Liver Transplant: Determining When and Why to Apply the Surgical Brakes
  • Regenerative Medicine: Repairing the Injured Spinal Cord
  • Rett Syndrome: Surveying Brain Patterns to Increase Disease Knowledge

January 2010

  • Cancer: Changing Current Understanding of Gene Function
  • Leukemia: New Population of Cells Discovered
  • Cancer Biology: Sensitizing ‘Tenacious’ Tumour Cells
  • Neurology: Detailing the Memory Process
  • Cardiology: Re-Examining Protective Properties of Beta-Blockers

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Previous issues of Net Results EXPRESS can be viewed in the archive.

     

 


   
 
 
 
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