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Princess Margaret Cancer Institute Techna Institute Toronto General Research Institute Toronto Rehabilitation Institute Toronto Western Research Institute

Princess Margaret Cancer Centre

Techna Institute

Toronto General Research Institute

Toronto Rehab Institute

Toronto Western Research Institute

  • Research foci: cancer— genomics, informatics, molecular biology, clinical trials, signalling pathways, structural biology and biophysics.
  • 376 scientists and clinician-scientists
  • $150M external funding
  • more

  • Headquartered at the Banting Building
  • Research foci: guided therapeutics, informatics and communication technologies, nanotechnology and radiochemistry, photonics, design and engineering for health
  • 50 scientists and clinician-scientists
  • more

  • Located at the Toronto General Hospital
  • Research foci: cardiology, transplantation, immunology and infectious disease
  • 256 scientists and clinician-scientists
  • $74M external funding
  • more

  • Located at Toronto Rehab
  • Research foci: rehabilitation sciences, cardiopulmonary fitness and mobility
  • 118 scientists and clinician-scientists
  • $9M external funding
  • more

  • Located at the Toronto Western Hospital
  • Research foci: Neural and visual sciences, musculoskeletal disease and community and population health
  • 161 scientists and clinician-scientists
  • $37M external funding
  • more

Neurological Disorders: Seizing Brain Activity
Nov 25, 2015

Neurological disorders, including Rett syndrome, neonatal encephalopathy, X-linked mental retardation and autism have something in common: patients with these disorders are more likely to experience recurrent seizures. Seizures are sudden rushes of electrical activity in the brain that can physically manifest as changes in how a person behaves—from a momentary lapse in attention to full-blown convulsions. Recent evidence suggests that MeCP2 deficiency and seizures are associated, but the underlying reason for this link remains unknown. Krembil Senior Scientist Dr. James Eubanks and Krembil Affiliate Scientist Dr. Liang Zhang co-led a study to determine how lower levels of MeCP2 could lead to seizures in an experimental model. 

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Cancer: Hospitalization Discrepancy
Nov 23, 2015

Before chemotherapy drugs can be used in real world settings, they must undergo testing in clinical trials. These trials provide important knowledge about potential side effects that range from mild to severe, including those that require hospitalization. While physicians use hospitalization rates to help decide which chemotherapy drug to prescribe, no explicit comparisons between rates in the real world versus those during clinical trials have ever been performed. A new study by Drs. Rebecca Prince (Clinical Research Fellow, PM Cancer Centre) and Monika Krzyzanowska (Medical Oncologist, PM Cancer Centre) sheds light on this issue.

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The ORT Times November Issue Now Available
Nov 20, 2015

Welcome to The ORT Times!

The UHN Office of Research Trainees (ORT) is proud to announce the November issue of The ORT Times! The ORT Times is a monthly e-newsletter focused on UHN trainees featuring news and editorials about trainee life, articles to help developing researchers get the most out of their training experience at UHN, tips on career development, and research training opportunities within and outside of UHN.

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