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Ontario Cancer Institute Toronto General Research Institute Toronto Rehabilitation Institute Toronto Western Research Institute
  • Located at the Princess Margaret Cancer Centre, Toronto, Ontario
  • Research foci: cancer— genomics, informatics, molecular biology, clinical trials, signalling pathways, structural biology and biophysics.
  • 361 scientists and clinician-scientists
  • $162M external funding
  • more
  • Located at the Toronto General Hospital, Toronto, Ontario
  • Research foci: cardiology, transplantation, immunology and infectious disease
  • 230 scientists and clinician-scientists
  • $73M external funding
  • more
  • Located at Toronto Rehab, Toronto, Ontario
  • Research foci: rehabilitation sciences, cardiopulmonary fitness and mobility
  • 119 scientists and clinician-scientists
  • $8M external funding
  • more
  • Located at the Toronto Western Hospital, Toronto, Ontario
  • Research foci: Neural and visual sciences, musculoskeletal disease and community and population health
  • 159 scientists and clinician-scientists
  • $35M external funding
  • more


The ORT Times August Issue Now Available
Aug 18, 2014

Welcome to The ORT Times!

The UHN Office of Research Trainees (ORT) is proud to announce the August 2014 ‘Summer Lite’ issue of The ORT Times! The ORT Times is a monthly e-newsletter for UHN trainees that features news and editorials about trainee life, articles to help developing researchers get the most out of their training experience at UHN, and tips on career development.

Read the full August 2014 issue online now.

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Parkinson's Disease: Negative Expectations Decrease Benefit of Therapy
Aug 13, 2014

A patient’s thoughts and expectations can impact the effectiveness of their therapy. The placebo effect is widely recognized in medical research. Here, a patient’s expectations can lead them to experience a benefit when they believe their treatment is effective. This phenomenon justifies the need for using a placebo or sugar pill (a pill that contains no active medication) comparator in clinical research trials evaluating new therapies. A little recognized and much less studied effect of patient expectation has been termed the lessebo effect. Here, clinical trial participants who know that they could receive either an active drug or a sugar pill experience a decreased benefit from the active drug.

A study published by TWRI Senior Scientist Dr. Anthony Lang demonstrated for the first time the presence and strength of the lessebo effect in clinical trials assessing the effectiveness of dopamine agonists, a class of drugs used to manage movement disturbances associated with Parkinson's disease (PD).

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Peter Pisters Announced as UHN's New CEO
Aug 11, 2014

UHN's Board of Trustees and the Selection Committee has concluded its international search for a new President and CEO, identifying Dr. Peter Pisters of MD Anderson.

"As a Canadian, I have always been proud of the health care offered to all citizens," said Dr. Pisters. "To return as President and CEO of UHN is a unique challenge and a privilege. I will do everything in my power to build on the legacy of those who have gone before me."

Dr. Pisters begins his role at UHN on January 1, 2015. He will bring with him a wide range of administrative and leadership experience from his current role at MD Anderson Cancer Center in Houston, Texas, where he is the Vice-President, Regional Care System. He is also an internationally renowned academic surgical oncologist with a specialty focus in sarcoma and gastrointestinal cancers, and an Executive Fellow in the Baldridge Performance Excellence Program of the US National Institute of Standards and Technology. Dr. Pisters is a graduate of The University of Western Ontario (MD) and Harvard University School of Public Health (MSc in Health Care Management).

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