Wright Cell Imaging Facility

 

 

 

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HeLa cell expressing endoplasmic reticulum targeted GFP and mitochondrially targeted DsRed2. This is a 5 min time course of an unusually dynamic cell.
The ER's motion shows the tubule branching, ring closure and sliding that was classically described by Lee & Chen (Cell, 1988,54(1):37-46).
The mitochondria also show very dynamic behaviour, at one point carving a path through the ER (starting  at 230s; right-middle). A mitochondrial fusion event can be seen also in frame 230s (centre, lower-left). 5µm scale bar.

 (T. Collins, Babraham Institute, UK).

Click here for 2 Mb movie

   
   

14/02/2006