Wright Cell Imaging Facility

The Wright Cell Imaging Facility has contributed to the following publications

 

Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Schut D, Fehlings MG. Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord. J Neurosci. 2010 Feb 3;30(5):1657-76. PMID: 20130176 [PUBMED]

Liu Y, Figley S, Spratt SK, Lee G, Ando D, Surosky R, Fehlings MG. An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury. Neurobiol Dis. 2010 Feb;37(2):384-93. PMID: 19879362 [PUBMED]

Schlichter LC, Kaushal V, Moxon-Emre I, Sivagnanam V, Vincent C. The Ca2+ activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro. J Neuroinflammation. 2010 Jan 14;7:4. PMID: 20074365 [PUBMED]

Shynlova O, Kwong R, Lye SJ. Mechanical stretch regulates hypertrophic phenotype of the myometrium during pregnancy. Reproduction. 2010 Jan;139(1):247-53. PMID: 19776098 [PUBMED]

Koeberle PD, Wang Y, Schlichter LC. Kv1.1 and Kv1.3 channels contribute to the degeneration of retinal ganglion cells after optic nerve transection in vivo. Cell Death Differ. 2010 Jan;17(1):134-44. PMID: 19696788 [PUBMED]

Moxon-Emre I, Schlichter LC. Evolution of inflammation and white matter injury in a model of transient focal ischemia. J Neuropathol Exp Neurol. 2010 Jan;69(1):1-15. PMID: 20010307 [PUBMED]

Chen D, Pacal M, Wenzel P, Knoepfler PS, Leone G, Bremner R. Division and apoptosis of E2f-deficient retinal progenitors. Nature. 2009 Dec 17;462(7275):925-9. PMID: 20016601 [PUBMED]

Shan Y, Liu B, Li L, Chang N, Li L, Wang H, Wang D, Feng H, Cheung C, Liao M, Cui T, Sugita S, Wan Q. Regulation of PINK1 by NR2B-containing NMDA receptors in ischemic neuronal injury. J Neurochem. 2009 Dec;111(5):1149-60. PMID: 19780893 [PUBMED]

Nag S, Manias JL, Stewart DJ. Pathology and new players in the pathogenesis of brain edema. Neuropathol Appl Acta Neuropathol. 2009 Aug;118(2):197-217. PMID: 19404652 [PUBMED]

Nag S, Manias JL, Stewart DJ. Expression of endothelial phosphorylated caveolin-1 is increased in brain injury. Neuropathol Appl Neurobiol. 2009 Aug;35(4):417-26. PMID: 19508446 [PUBMED]

Baptiste DC, Austin JW, Zhao W, Nahirny A, Sugita S, Fehlings MG. Systemic polyethylene glycol promotes neurological recovery and tissue sparing in rats after cervical spinal cord injury. J Neuropathol Exp Neurol. 2009 Jun;68(6):661-76. PMID: 19458542 [PUBMED]

Erwin WM, Las Heras F, Islam D, Fehlings MG, Inman RD. The regenerative capacity of the notochordal cell: tissue constructs generated in vitro under hypoxic conditions. J Neurosurg Spine. 2009 Jun;10(6):513-21. PMID: 19558283 [PUBMED]

Olah ME, Jackson MF, Li H, Perez Y, Sun HS, Kiyonaka S, Mori Y, Tymianski M, MacDonald JF. Ca2+-dependent induction of TRPM2 currents in hippocampal neurons. J Physiol. 2009 Mar 1;587(Pt 5):965-79. PMID: 19124544 [PUBMED]

Wasserman JK, Schlichter LC. White matter injury in young and aged rats after intracerebral hemorrhage. Exp Neurol. 2008 Dec;214(2):266-75. PMID: 18848934 [PUBMED]

Wasserman JK, Yang H, Schlichter LC. Glial responses, neuron death and lesion resolution after intracerebral hemorrhage in young vs. aged rats. Eur J Neurosci. 2008 Oct;28(7):1316-28. PMID: 18973558 [PUBMED]

Mothe AJ, Tator CH. Transplanted neural stem/progenitor cells generate myelinating oligodendrocytes and Schwann cells in spinal cord demyelination and dysmyelination. Exp Neurol. 2008 Sep;213(1):176-90. PMID: 18586031 [PUBMED]

Visanji NP, Orsi A, Johnston TH, Howson PA, Dixon K, Callizot N, Brotchie JM, Rees DD. PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. FASEB J. 2008 Jul;22(7):2488-97. PMID: 18364399 [PUBMED]

Kulbatski I, Mothe AJ, Parr AM, Kim H, Kang CE, Bozkurt G, Tator CH. Glial precursor cell transplantation therapy for neurotrauma and multiple sclerosis. Prog Histochem Cytochem. 2008;43(3):123-76. PMID: 18706353 [PUBMED]

Yeung D, Manias JL, Stewart DJ, Nag S. Decreased junctional adhesion molecule-A expression during blood-brain barrier breakdown. Acta Neuropathol. 2008 Jun;115(6):635-42. PMID: 18357461 [PUBMED]

Jugloff DG, Vandamme K, Logan R, Visanji NP, Brotchie JM, Eubanks JH. Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice. Hum Mol Genet. 2008 May 15;17(10):1386-96. PMID: 18223199 [PUBMED]

Lee J, Gomez-Ramirez J, Johnston TH, Visanji N, Brotchie JM. Receptor-activity modifying protein 1 expression is increased in the striatum following repeated L-DOPA administration in a 6-hydroxydopamine lesioned rat model of Parkinson's disease. Synapse. 2008 Apr;62(4):310-3. PMID: 18241048 [PUBMED]

Kaushal V, Schlichter LC. Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. J Neurosci. 2008 Feb 27;28(9):2221-30. PMID: 18305255 [PUBMED]

Wasserman JK, Zhu X, Schlichter LC. Evolution of the inflammatory response in the brain following intracerebral hemorrhage and effects of delayed minocycline treatment. Brain Res. 2007 Nov 14;1180:140-54. PMID: 17919462 [PUBMED]

Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF. TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16323-8. PMID: 17913893 [PUBMED]

Seif GI, Nomura H, Tator CH. Retrograde axonal degeneration "dieback" in the corticospinal tract after transection injury of the rat spinal cord: a confocal microscopy study. J Neurotrauma. 2007 Sep;24(9):1513-28. PMID: 17892412 [PUBMED]

Cui H, Hayashi A, Sun HS, Belmares MP, Cobey C, Phan T, Schweizer J, Salter MW, Wang YT, Tasker RA, Garman D, Rabinowitz J, Lu PS, Tymianski M. PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. J Neurosci. 2007 Sep 12;27(37):9901-15. PMID: 17855605 [PUBMED]

Chu GK, Yu W, Fehlings MG. The p75 neurotrophin receptor is essential for neuronal cell survival and improvement of functional recovery after spinal cord injury. Neuroscience. 2007 Sep 7;148(3):668-682. PMID: 17706365 [PUBMED]

Wasserman JK, Schlichter LC. Minocycline protects the blood-brain barrier and reduces edema following intracerebral hemorrhage in the rat. Exp Neurol. 2007 Oct;207(2):227-37. PMID: 17698063 [PUBMED]

Khanna R, Li Q, Schlichter LC, Stanley EF. The transmitter release-site CaV2.2 channel cluster is linked to an endocytosis coat protein complex. Eur J Neurosci. 2007 Aug;26(3):560-74. PMID: 17686037 [PUBMED]

Khanna R, Li Q, Bewersdorf J, Stanley EF. The presynaptic CaV2.2 channel-transmitter release site core complex. Eur J Neurosci. 2007 Aug;26(3):547-59. PMID: 17686036 [PUBMED]

Chen D, Opavsky R, Pacal M, Tanimoto N, Wenzel P, Seeliger MW, Leone G, Bremner R. Rb-Mediated Neuronal Differentiation through Cell-Cycle-Independent Regulation of E2f3a. PLoS Biol. 2007 Jul 3;5(7):e179 PMID: 17608565 [PUBMED]

Fujita Y, Xu A, Xie L, Arunachalam L, Chou TC, Jiang T, Chiew SK, Kourtesis J, Wang L, Gaisano HY, Sugita S. Ca2+-dependent activator protein for secretion 1 is critical for constitutive and regulated exocytosis but not for loading of transmitters into dense core vesicles. J Biol Chem. 2007 Jul 20;282(29):21392-403. PMID: 17540763 [PUBMED]

Parr AM, Kulbatski I, Tator CH. Transplantation of adult rat spinal cord stem/progenitor cells for spinal cord injury. J Neurotrauma. 2007 May;24(5):835-45. PMID: 17518538 [PUBMED]

McClellan KA, Ruzhynsky VA, Douda DN, Vanderluit JL, Ferguson KL, Chen D, Bremner R, Park DS, Leone G, Slack RS. Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. Mol Cell Biol. 2007 Jul;27(13):4825-43. PMID: 17452454 [PUBMED]

Zhang G, Jung BP, Ho W, Jugloff DG, Cheung HH, Gurd JW, Wallace MC, Eubanks JH. Isolation and characterization of LCHN: a novel factor induced by transient global ischemia in the adult rat hippocampus. J Neurochem. 2007 Apr;101(1):263-73. PMID: 17394467 [PUBMED]

Eftekharpour E, Karimi-Abdolrezaee S, Wang J, El Beheiry H, Morshead C, Fehlings MG. Myelination of congenitally dysmyelinated spinal cord axons by adult neural precursor cells results in formation of nodes of Ranvier and improved axonal conduction. J Neurosci. 2007 Mar 28;27(13):3416-28. PMID: 17392458 [PUBMED]

Jung BP, Purushotham D, Eubanks JH. Identification of a murine methyl cytosine phosphate guanine binding domain-containing factor 3 (MBD3) promoter segment sufficient for driving reporter gene expression in neurons in vitro and in vivo. Neuroscience. 2007 Mar 30;145(3):1016-25. PMID: 17289276 [PUBMED]

Wasserman JK, Schlichter LC. Neuron death and inflammation in a rat model of intracerebral hemorrhage: effects of delayed minocycline treatment. Brain Res. 2007 Mar 9;1136(1):208-18. PMID: 17223087 [PUBMED]

Kaushal V, Koeberle PD, Wang Y, Schlichter LC. The Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration. J Neurosci. 2007 Jan 3;27(1):234-44. PMID: 17202491 [PUBMED]

Li G, Han L, Chou TC, Fujita Y, Arunachalam L, Xu A, Wong A, Chiew SK, Wan Q, Wang L, Sugita S. RalA and RalB function as the critical GTP sensors for GTP-dependent exocytosis. J Neurosci. 2007 Jan 3;27(1):190-202. PMID: 17202486 [PUBMED]

Khanna R, Li Q, Stanley EF. 'Fractional recovery' analysis of a presynaptic synaptotagmin 1-anchored endocytic protein complex. PLoS ONE. 2006 Dec 20;1:e67. PMID: 17183698 [PUBMED]

Al Chawaf A, St Amant K, Belsham D, Lovejoy DA. Regulation of neurite growth in immortalized mouse hypothalamic neurons and rat hippocampal primary cultures by teneurin C-terminal-associated peptide-1. Neuroscience. 2007 Feb 23;144(4):1241-54. PMID: 17174479 [PUBMED]

Kulbatski I, Mothe AJ, Keating A, Hakamata Y, Kobayashi E, Tator CH. Oligodendrocytes and radial glia derived from adult rat spinal cord progenitors: morphological and immunocytochemical characterization. J Histochem Cytochem. 2007 Mar;55(3):209-22. PMID: 17101728 [PUBMED]

Lau A, Arundine M, Sun HS, Jones M, Tymianski M. Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury. J Neurosci. 2006 Nov 8;26(45):11540-53. PMID: 17093075 [PUBMED]  

Khanna R, Li Q, Sun L, Collins TJ, Stanley EF. N type Ca2+ channels and RIM scaffold protein covary at the presynaptic transmitter release face but are components of independent protein complexes. Neuroscience. 2006 Jul 21;140(4):1201-8. Epub 2006 Jun 6. PMID: 16757118 [PUBMED]  

Liu B, Liao M, Mielke JG, Ning K, Chen Y, Li L, El-Hayek YH, Gomez E, Zukin RS, Fehlings MG, Wan Q. Ischemic insults direct glutamate receptor subunit 2-lacking AMPA receptors to synaptic sites. J Neurosci. 2006 May 17;26(20):5309-19 PMID: 16707783 [PUBMED]

Leung YM, Ahmed I, Sheu L, Tsushima RG, Diamant NE, Gaisano HY. Two populations of pancreatic islet alpha-cells displaying distinct Ca2+ channel properties. Biochem Biophys Res Commun. 2006 Jun 23;345(1):340-4. PMID: 16678791 [PUBMED]

Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Morshead CM, Fehlings MG. Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. J Neurosci. 2006 Mar 29;26(13):3377-89. PMID: 16571744 [PUBMED]

Sun L, Li Q, Khanna R, Chan AW, Wong F, Stanley EF. Transmitter release face Ca2+ channel clusters persist at isolated presynaptic terminals. Eur J Neurosci. 2006 Mar;23(5):1391-6 PMID: 16553800 [PUBMED]

Livne-Bar I, Pacal M, Cheung MC, Hankin M, Trogadis J, Chen D, Dorval KM, Bremner R. Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina. Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):4988-93. PMID: 16547132 [PUBMED]

Khanna R, Sun L, Li Q, Guo L, Stanley EF. Long splice variant N type calcium channels are clustered at presynaptic transmitter release sites without modular adaptor proteins. Neuroscience. 2006;138(4):1115-25. PMID: 16473471 [PUBMED]

Leung YM, Ahmed I, Sheu L, Gao X, Hara M, Tsushima RG, Diamant NE, Gaisano HY. Insulin regulates islet alpha-cell function by reducing KATP channel sensitivity to adenosine 5'-triphosphate inhibition. Endocrinology. 2006 May;147(5):2155-62. PMID: 16455778 [PUBMED]

Sinha K, Karimi-Abdolrezaee S, Velumian AA, Fehlings MG. Functional changes in genetically dysmyelinated spinal cord axons of shiverer mice: role of juxtaparanodal Kv1 family K+ channels. J Neurophysiol. 2006 Mar;95(3):1683-95. PMID: 16319208 [PUBMED]

Cheung YH, Chang NH, Cai YC, Bonventi G, MacLeod R, Wither JE. Functional interplay between intrinsic B and T cell defects leads to amplification of autoimmune disease in New Zealand black chromosome 1 congenic mice. J Immunol. 2005 Dec 15;175(12):8154-64. PMID: 16339554 [PUBMED]

Li G, Lee D, Wang L, Khvotchev M, Chiew SK, Arunachalam L, Collins T, Feng ZP, Sugita S. N-terminal insertion and C-terminal ankyrin-like repeats of alpha-latrotoxin are critical for Ca2+-dependent exocytosis. J Neurosci. 2005 Nov 2;25(44):10188-97. PMID: 16267226 [PUBMED]

Wither JE, Loh C, Lajoie G, Heinrichs S, Cai YC, Bonventi G, MacLeod R. Colocalization of expansion of the splenic marginal zone population with abnormal B cell activation and autoantibody production in B6 mice with an introgressed New Zealand Black chromosome 13 interval. J Immunol. 2005 Oct 1;175(7):4309-19. PMID: 16177071 [PUBMED]

Fordyce CB, Jagasia R, Zhu X, Schlichter LC. Microglia Kv1.3 channels contribute to their ability tokill neurons. J Neurosci. 2005 Aug 3;25(31):7139-49. PMID: 16079396 [PUBMED]

Jugloff DG, Jung BP, Purushotham D, Logan R, Eubanks JH. Increased dendritic complexity and axonal length in cultured mouse cortical neurons overexpressing methyl-CpG-binding protein MeCP2. Neurobiol Dis. 2005 Jun-Jul;19(1-2):18-27. PMID: 15837557 [PUBMED]

Eftekharpour E, Karimi-Abdolrezaee S, Sinha K, Velumian AA, Kwiecien JM, Fehlings MG. Structural and functional alterations of spinal cord axons in adult Long Evans Shaker (LES) dysmyelinated rats. Exp Neurol. 2005 Jun;193(2):334-49. PMID: 15869936 [PUBMED]

Zou S, Li L, Pei L, Vukusic B, Van Tol HH, Lee FJ, Wan Q, Liu F. Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity. J Neurosci. 2005 Apr 27;25(17):4385-95. PMID: 15858065 [PUBMED]

Ning K, Pei L, Liao M, Liu B, Zhang Y, Jiang W, Mielke JG, Li L, Chen Y, El-Hayek YH, Fehlings MG, Zhang X, Liu F, Eubanks J, Wan Q. Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN. J Neurosci. 2004 Apr 21;24(16):4052-60. PMID: 15102920 [PUBMED]

Mothe AJ, Tator CH. Proliferation, migration, and differentiation of endogenous ependymal region stem/progenitor cells following minimal spinal cord injury in the adult rat. Neuroscience. 2005;131(1):177-87. PMID: 15680701 [PUBMED]

Li Q, Lau A, Morris TJ, Guo L, Fordyce CB, Stanley EF. A Syntaxin 1, G{alpha}o, and N-Type Calcium Channel Complex at a Presynaptic Nerve Terminal: Analysis by Quantitative Immunocolocalization. Journal of Neuroscience 2004 24: 4070-4081. [PUBMED]

Chen D, Livne-Bar I, Vanderluit JL, Slack RS, Agochiya M and Bremner R. Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma. Cancer Cell 2004 5: 539-551. [PUBMED]

Karimi-Abdolrezaee S, Eftekharpour E,  Fehlings MG. Temporal and spatial patterns of Kv1.1 and Kv1.2 protein and gene expression in spinal cord white matter after acute and chronic spinal cord injury in rats: implications for axonal pathophysiology after neurotrauma. European Journal of Neuroscience. 2004 19: 577-589. [PUBMED]

Jung BP, Jugloff DG, Zhang G, Logan R, Brown S, Eubanks JH. The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells. J Neurobiol. 2003 55:86-96. [PUBMED]

Morris TJ, Stanley EF. A simple method for immunocytochemical staining with multiple rabbit polyclonal antibodies. J Neurosci Methods. 2003 127:149-55. [PUBMED]

01/12/2007