|
Unlike
other microdissection systems, the
P.A.L.M. system uses ablative photodecomposition to 'microdissect'
biological tissue without any heating; and radiative pressure forces
to 'catapult' the
desired tissue in to a standard collection tube. This helps keep
costs down since specialised collection caps are not required.
The absence of
physical contact prevents contamination and the absence of any heating
prevents denaturation of nucleic acids and enzyme activity is retained.
The absence of any heating means that live cells can also be harvested.
Figure right. H&E stained canine kidney
section before, after microdissection and
after laser-pressure catapulting. Specimen
provided by H. Arthurs
(Carl Zeiss Canada) |
